Do you want to get your laboratory on the list?
Please contact Ken Keeler at 936-6663 (kkeeler@umich.edu)
Do you want to get your laboratory on the list?
Please contact Ken Keeler at 936-6663 (kkeeler@umich.edu)
Our research focuses on the translational targeted cancer-drug development and drug delivery systems in Thyroid cancer, head and neck squamous cell cancer, melanoma and breast cancer. Our clinical interests include endocrine surgery specifically thyroid surgery for benign and malignant disease, minimally invasive parathyroid surgery and adrenalectomy, as well as surgery for advanced melanomas including hyperthermic isolated limb perfusion. We employ molecular biology and cell culture techniques and waste generated is disposed of adhering to U-M EHS guidelines.
This program allowed us to address on small changes to bring big impact on the environment, such as energy conservation, recycling and many other initiatives. Now more than ever it is important to do what we can to conserve energy and protect the environment, and this program allows our lab to do both on a daily basis. We recommend it to every lab on our campus Dr. Chitra Subramanian, Lab Manager
The central goal of our studies is to unravel the molecular and cellular mechanisms of diseases that disrupt the motor system. In exploring these diseases, we are also interested in understanding a fundamental question relevant to CNS disease generally: what factors determine the selective vulnerability of particular cell types or circuits to particular insults? Our primary focus is on Parkinson’s disease and DYT1 dystonia. For each of these projects, we focus our efforts on disease genes that cause these disorders, employing a range of molecular, cellular, and whole animal studies to dissect the normal role of disease proteins, and how pathogenic mutations lead to disease.
I was not aware of the large implications that many small changes in a lab can have on the environment, such as increasing our -80 degree freezer to -70 degrees, until joining the Sustainable Lab program. Now more than ever it is important to do what we can to conserve energy and protect the environment, and this program allows our lab to do both on a daily basis. Stephanie Mrowczynski, Technician
Our research focuses on the mechanisms underlying immune-mediated lung injury with emphasis on understanding epithelial injury and mesenchymal activation in Idiopathic Pulmonary Fibrosis (IPF) and chronic rejection occurring post-lung transplantation. IPF is the most common form on interstitial lung diseases (ILD) with an ‘orphan disease” status. It has no known etiology or an effective treatment modality that can reverse the progression of the disease. Our work focuses on the roles of IL-17A in epithelial injury and mesenchymal activation and complement activation in epithelial injury and tissue repair. We employ techniques like cell culture, QPCR, Western blot, Fluorescent staining and micro biology protocols. The solid and hazardous waste generated from our lab is being disposed of adhering to U-M EHS guidelines.
“The Vittal lab is glad to participate in the Sustainable Lab program, which helps our lab take steps towards creating a safe eco-friendly laboratory environment.” -- Ellyse Cipolla, Lab Manager
Our lab investigates mechanisms that contribute to bone metastasis of prostate cancer. We also have active interest in the contribution of aging to the development of genitourinary disease, and employ several animal models (including zebrafish) to pursue these studies. The solid and hazardous waste generated from our lab is being disposed of in adherence to U-M EHS guidelines.
“We are happy to participate in the Sustainable Lab program, and we have taken steps to create a safer and more sustainable laboratory environment. We recycle waste when appropriate, purchase eco-friendly products, and turn off and unplug unused devices to reduce energy consumption. By participating in various campus reuse programs, we try to re-use reagents, materials, and equipment before purchasing new ones. We are glad to contribute to U-M’s campus-wide goals to improve up on sustainability” -- June Escara-Wilke, Greg Shelley: Lab Managers
Our work specializes in the study of microbial consortia. As a result, we do considerable genetic work, including various standard biological procedures that include but are not limited to PCR, gel electrophoresis, genetic transformations, HPLC and fluorescent microscopy. We also use various microfluidic techniques to study microbial communities in droplets for high throughput applications. Hazardous and non-hazardous waste generated in our lab is disposed of adhering to U-M EHS guidelines.
“Functionalized sustainability initiatives demand a shared vision as no single actor is capable of building a sustainable enterprise. Instead, they necessitate making our collective diversity work for us rather than against us. The sustainable lab program facilitates this work by enabling members from across the research community to make conscious behavioral changes that reduce waste and ultimately promote sustainable laboratory practices.”
David Carruthers, Sustainability Liaison
Research in our lab focuses on the role of the oral spirochete Treponema denticola in the development of periodontal diseases. The studies involve molecular characterization of spirochete surface-expressed and secreted proteins and their interactions with host tissue components. These studies, which involve both genetic and biochemical analyses, will contribute to the understanding of microbe-host interactions in the etiology of periodontal diseases, as well as to basic knowledge of the molecular biology of pathogenic spirochetes. Waste generated in our lab is disposed of adhering to EHS guidelines.
“With the help of the Sustainable Lab program staff, our wet lab space has taken many steps to create a safer and more sustainable laboratory environment. We recycle waste when appropriate, purchase eco-friendly products, and turn off and unplug unused devices to reduce our energy consumption. By utilizing the Chemical Reuse program, we try to first implement used materials before purchasing new ones. It is a pleasure to participate in this program to help U-M reach its campus-wide sustainability goals” -- Paula Goetting, Lab Manager
Our research interests include creating and maintain a Digital Pathology Image Repository for renal diseases and mouse models of glomerular injury, with a focus on podocyte biology. We employ various computational techniques to analyze damage to specific portions of the kidney. To investigate the key pathogenic mechanisms of mouse disease models, we are employing systems biology approaches to identify cross-species, human-mouse shared transcriptional networks. We employ techniques such as PCR, IHC, IF protocols, Western blots etc., Solid and hazardous waste generated in our lab in disposed of following EHS guidelines.
“With the help of the Sustainable Lab program staff, our wet lab space has taken many steps to create a safer and more sustainable laboratory environment. We have eliminated ethidium bromide and use the SYBR Safe gel dye alternative, recycle waste when appropriate, purchase eco-friendly products, and turn off and unplug unused devices to reduce our energy consumption. By utilizing the Chemical Reuse program, we try to first implement used materials before purchasing new ones. It is a pleasure to participate in this program to help U-M reach its campus-wide sustainability goals”
-- Stephanie Wylie, Lab Manager
Our lab performs clinical operations for the Michigan Medical facility. We perform PCR testing and employ the following equipment: Hologic Panther, Roche Cobas X4800, Focus Integrated Cyclers, Abbott m2000sp and m2000rt and Eli Tech.
“Being enrolled in the Sustainable Laboratory program has given us the opportunity to lessen our carbon footprint as we can reduce our waste, save money on electricity, and disposal of harmful reagents into the environment. We no longer use ethidium bromide, and also use the Chemical Reuse program.” -- AJ Dudus, Medical Technologist
Our lab studies the interplay of cellular RNA trafficking and retroviral replication steps as well as mechanisms of HIV-1 and other retroviral genetic variation. We use a number of genetic, molecular and biological techniques, such as PCR, gel electrophoresis, western blot, northern blot, cellular transformation, and transfection. We began using Gel Red as a safer product to replace toxic ethidium bromide in gel work. We’ve also utilized various recycling opportunities supplied by the Sustainable Lab Program. Waste generated in our lab is disposed of adhering to OSEH guidelines.
“I am so glad that the University of Michigan has a sustainable lab program. Our university is a leader in so many areas and I’m glad sustainability is one of them. The sharing of resources (like equipment), transitioning to less toxic reagents, and recycling alternatives to traditional waste streams are all wonderful improvement on the laboratory practices used in the past.
Jennifer Medlin
Our laboratory uses a combination of biochemical and biophysical approaches to study the structures, mechanisms, and substrate specificities of a variety of enzymes, with a particularly focus on chromatin modifying enzymes. Techniques used in the lab include crystallography, enzyme kinetics, calorimetry, and other biophysical and biochemical approaches. Current projects include: Structural and functional studies of chromatin modifying enzymes, mechanisms of S-Adenosylmethionine dependent methyltransferaces and structure function studies for a target anti-fungal drug design. The solid and hazardous waste generated from our lab is being disposed of adhering to U-M EHS guidelines.
“We are happy to participate in the Sustainable Lab program, and we have taken steps to create a safer and more sustainable laboratory environment. We recycle waste when appropriate, purchase eco-friendly products, and turn off and unplug unused devices to reduce energy consumption. By participating in various campus reuse programs, we try to re-use reagents, materials, and equipment before purchasing new ones. We are glad to contribute to U-M’s campus-wide goals to improve up on sustainability” –Prof. Raymond Trievel, Principal Investigator.